IO BIOTECH INC

Ticker: IOBT CUSIP: 449778109 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 44,757 Value ($000) $27 Avg Close $0.74 Range $0.35 - $1.23

Q2 2025

Shares 10,385 Value ($000) $14 Avg Close $1.15 Range $0.83 - $1.70

Q4 2024

Shares 12,384 Value ($000) $11 Avg Close $0.99 Range $0.66 - $1.36

Q2 2023

Shares 13,020 Value ($000) $25 Avg Close $1.95 Range $1.56 - $2.64

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	44,757	$27	$0.74	$0.35 - $1.23
Q2 2025	10,385	$14	$1.15	$0.83 - $1.70
Q4 2024	12,384	$11	$0.99	$0.66 - $1.36
Q2 2023	13,020	$25	$1.95	$1.56 - $2.64