IDERA PHARMACEUTICALS INC

CUSIP: 45168K306 Class: CMN

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 128,920 Value ($000) $237 Avg Close — Range —
Q4 2017
Shares 303,204 Value ($000) $640 Avg Close — Range —
Q4 2013
Shares 18,639 Value ($000) $86 Avg Close — Range —