IDERA PHARMACEUTICALS INC

CUSIP: 45168K306 Class: CMN

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017
Shares 16,220 Value ($000) $34 Avg Close — Range —
Q3 2017
Shares 21,234 Value ($000) $47 Avg Close — Range —
Q4 2016
Shares 18,019 Value ($000) $27 Avg Close — Range —