IDERA PHARMACEUTICALS INC

CUSIP: 45168K306 Class: CMN

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018
Shares 31,400 Value ($000) $41 Avg Close — Range —
Q1 2018
Shares 25,000 Value ($000) $46 Avg Close — Range —
Q4 2017
Shares 43,600 Value ($000) $92 Avg Close — Range —