IMPEL PHARMACEUTICALS INC

CUSIP: 45258K109 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021
Shares 142,098 Value ($000) $1,226 Avg Close — Range —
Q2 2021
Shares 10,043 Value ($000) $89 Avg Close — Range —