INOTEK PHARMACEUTICALS CORP

CUSIP: 45780V102 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 38,300 Value ($000) $283 Avg Close — Range —
Q4 2015
Shares 63,400 Value ($000) $718 Avg Close — Range —
Q3 2015
Shares 79,800 Value ($000) $764 Avg Close — Range —