INNOVIVA INC

Ticker: INVA CUSIP: 45781M101 Class: EQTY

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 839,865 Value ($000) $16,789 Avg Close $19.53 Range $16.52 - $22.76

Q3 2025

Shares 522,242 Value ($000) $9,531 Avg Close $19.50 Range $17.55 - $21.13

Q2 2025

Shares 331,886 Value ($000) $6,668 Avg Close $19.23 Range $16.67 - $22.00

Q1 2025

Shares 667,585 Value ($000) $12,103 Avg Close $17.93 Range $17.01 - $19.39

Q4 2024

Shares 262,739 Value ($000) $4,559 Avg Close $19.20 Range $17.28 - $21.28

Q3 2024

Shares 483,812 Value ($000) $9,342 Avg Close $18.43 Range $16.18 - $20.19

Q2 2024

Shares 539,724 Value ($000) $8,851 Avg Close $15.51 Range $14.33 - $16.52

Q1 2024

Shares 549,226 Value ($000) $8,370 Avg Close $15.71 Range $14.48 - $16.86

Q4 2023

Shares 370,914 Value ($000) $5,949 Avg Close $13.98 Range $12.22 - $16.43

Q3 2023

Shares 288,546 Value ($000) $3,748 Avg Close $12.98 Range $12.33 - $13.89

Q2 2023

Shares 367,328 Value ($000) $4,676 Avg Close $12.51 Range $11.23 - $13.90

Q1 2023

Shares 17,791 Value ($000) $200 Avg Close $12.13 Range $10.64 - $13.80

Q4 2022

Shares 177,386 Value ($000) $2,350 Avg Close $13.15 Range $11.58 - $13.89

Q2 2022

Shares 414,331 Value ($000) $6,116 Avg Close $16.38 Range $14.06 - $20.71

Q1 2022

Shares 814,403 Value ($000) $15,759 Avg Close $17.86 Range $15.08 - $20.48

Q4 2021

Shares 411,978 Value ($000) $7,107 Avg Close $17.04 Range $15.79 - $18.97

Q3 2021

Shares 301,602 Value ($000) $5,040 Avg Close $14.96 Range $12.91 - $17.45

Q3 2020

Shares 31,273 Value ($000) $327 Avg Close $12.71 Range $10.32 - $14.64

Q2 2020

Shares 73,701 Value ($000) $1,030 Avg Close $13.60 Range $11.05 - $15.62

Q1 2020

Shares 93,803 Value ($000) $1,103 Avg Close $13.23 Range $7.58 - $15.35

Q4 2019

Shares 67,400 Value ($000) $954 Avg Close $12.27 Range $10.07 - $14.50

Q1 2019

Shares 14,235 Value ($000) $200 Avg Close $16.19 Range $13.55 - $20.54

Q4 2018

Shares 300,877 Value ($000) $5,250 Avg Close $16.24 Range $13.93 - $18.60

Q1 2018

Shares 85,000 Value ($000) $1,417 Avg Close $15.43 Range $13.52 - $17.21

Q4 2017

Shares 40,271 Value ($000) $571 Avg Close $13.34 Range $11.47 - $14.87

Q3 2017

Shares 117,569 Value ($000) $1,660 Avg Close $13.22 Range $11.88 - $14.48

Q1 2017

Shares 83,106 Value ($000) $1,149 Avg Close $11.77 Range $10.30 - $14.05

Q3 2016

Shares 149,455 Value ($000) $1,643 Avg Close $11.67 Range $10.48 - $13.37

Q2 2016

Shares 126,105 Value ($000) $1,328 Avg Close $11.83 Range $9.78 - $14.15

Q1 2016

Shares 76,921 Value ($000) $968 Avg Close $10.97 Range $7.56 - $13.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	839,865	$16,789	$19.53	$16.52 - $22.76
Q3 2025	522,242	$9,531	$19.50	$17.55 - $21.13
Q2 2025	331,886	$6,668	$19.23	$16.67 - $22.00
Q1 2025	667,585	$12,103	$17.93	$17.01 - $19.39
Q4 2024	262,739	$4,559	$19.20	$17.28 - $21.28
Q3 2024	483,812	$9,342	$18.43	$16.18 - $20.19
Q2 2024	539,724	$8,851	$15.51	$14.33 - $16.52
Q1 2024	549,226	$8,370	$15.71	$14.48 - $16.86
Q4 2023	370,914	$5,949	$13.98	$12.22 - $16.43
Q3 2023	288,546	$3,748	$12.98	$12.33 - $13.89
Q2 2023	367,328	$4,676	$12.51	$11.23 - $13.90
Q1 2023	17,791	$200	$12.13	$10.64 - $13.80
Q4 2022	177,386	$2,350	$13.15	$11.58 - $13.89
Q2 2022	414,331	$6,116	$16.38	$14.06 - $20.71
Q1 2022	814,403	$15,759	$17.86	$15.08 - $20.48
Q4 2021	411,978	$7,107	$17.04	$15.79 - $18.97
Q3 2021	301,602	$5,040	$14.96	$12.91 - $17.45
Q3 2020	31,273	$327	$12.71	$10.32 - $14.64
Q2 2020	73,701	$1,030	$13.60	$11.05 - $15.62
Q1 2020	93,803	$1,103	$13.23	$7.58 - $15.35
Q4 2019	67,400	$954	$12.27	$10.07 - $14.50
Q1 2019	14,235	$200	$16.19	$13.55 - $20.54
Q4 2018	300,877	$5,250	$16.24	$13.93 - $18.60
Q1 2018	85,000	$1,417	$15.43	$13.52 - $17.21
Q4 2017	40,271	$571	$13.34	$11.47 - $14.87
Q3 2017	117,569	$1,660	$13.22	$11.88 - $14.48
Q1 2017	83,106	$1,149	$11.77	$10.30 - $14.05
Q3 2016	149,455	$1,643	$11.67	$10.48 - $13.37
Q2 2016	126,105	$1,328	$11.83	$9.78 - $14.15
Q1 2016	76,921	$968	$10.97	$7.56 - $13.21