INVITAE CORP

CUSIP: 46185L103 Class: Common Stock

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 440,000 Value ($000) $4,866 Avg Close — Range —
Q4 2016
Shares 500,000 Value ($000) $3,970 Avg Close — Range —