IONIS PHARMACEUTICALS INC

CUSIP: 462222AD2 Class: NOTE 4/0

FMR LLC's Holding History (CIK: 0000315066)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025
Shares 4,739,000 Value ($000) $6,492 Avg Close — Range —
Q3 2025
Shares 7,422,000 Value ($000) $9,107 Avg Close — Range —
Q2 2025
Shares 7,848,000 Value ($000) $7,879 Avg Close — Range —
Q1 2025
Shares 7,848,000 Value ($000) $7,695 Avg Close — Range —
Q4 2024
Shares 7,848,000 Value ($000) $7,558 Avg Close — Range —
Q3 2024
Shares 7,358,000 Value ($000) $7,338 Avg Close — Range —