IOVANCE BIOTHERAPEUTICS INC

Ticker: IOVA CUSIP: 462260100 Class: COM

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 2,610,510 Value ($000) $24,826 Avg Close $9.71 Range $8.26 - $11.36

Q4 2018

Shares 2,720,452 Value ($000) $24,076 Avg Close $9.64 Range $7.26 - $12.30

Q3 2018

Shares 1,121,153 Value ($000) $12,613 Avg Close $14.19 Range $11.20 - $18.25

Q2 2018

Shares 1,121,153 Value ($000) $14,351 Avg Close $14.62 Range $12.20 - $17.20

Q1 2018

Shares 659,059 Value ($000) $11,138 Avg Close $15.14 Range $7.85 - $19.90

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	2,610,510	$24,826	$9.71	$8.26 - $11.36
Q4 2018	2,720,452	$24,076	$9.64	$7.26 - $12.30
Q3 2018	1,121,153	$12,613	$14.19	$11.20 - $18.25
Q2 2018	1,121,153	$14,351	$14.62	$12.20 - $17.20
Q1 2018	659,059	$11,138	$15.14	$7.85 - $19.90