IOVANCE BIOTHERAPEUTICS INC

Ticker: IOVA CUSIP: 462260100 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 14,040 Value ($000) $38 Avg Close $2.31 Range $1.76 - $2.99

Q2 2025

Shares 45,858 Value ($000) $79 Avg Close $2.49 Range $1.64 - $3.73

Q2 2024

Shares 11,483 Value ($000) $92 Avg Close $10.72 Range $7.59 - $14.77

Q2 2017

Shares 13,763 Value ($000) $101 Avg Close $6.36 Range $4.90 - $7.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	14,040	$38	$2.31	$1.76 - $2.99
Q2 2025	45,858	$79	$2.49	$1.64 - $3.73
Q2 2024	11,483	$92	$10.72	$7.59 - $14.77
Q2 2017	13,763	$101	$6.36	$4.90 - $7.50