IOVANCE BIOTHERAPEUTICS INC

Ticker: IOVA CUSIP: 462260100 Class: COM

JANE STREET GROUP, LLC's Holding History (CIK: 0001595888)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,583,810 Value ($000) $9,784 Avg Close $2.31 Range $1.76 - $2.99

Q3 2025

Shares 1,413,662 Value ($000) $3,068 Avg Close $2.36 Range $1.67 - $4.33

Q2 2025

Shares 2,007,571 Value ($000) $3,453 Avg Close $2.49 Range $1.64 - $3.73

Q1 2025

Shares 121,090 Value ($000) $403 Avg Close $5.16 Range $3.19 - $8.15

Q4 2024

Shares 295,228 Value ($000) $2,185 Avg Close $9.27 Range $7.05 - $12.51

Q3 2024

Shares 116,970 Value ($000) $1,098 Avg Close $9.47 Range $7.11 - $12.50

Q2 2024

Shares 1,030,312 Value ($000) $8,263 Avg Close $10.72 Range $7.59 - $14.77

Q1 2024

Shares 1,021,067 Value ($000) $15,132 Avg Close $11.64 Range $7.34 - $18.33

Q4 2023

Shares 522,561 Value ($000) $4,248 Avg Close $5.23 Range $3.21 - $9.03

Q3 2023

Shares 549,915 Value ($000) $2,502 Avg Close $6.53 Range $4.36 - $8.82

Q2 2023

Shares 402,317 Value ($000) $2,832 Avg Close $7.16 Range $5.28 - $9.36

Q1 2023

Shares 65,684 Value ($000) $401 Avg Close $6.90 Range $5.39 - $8.49

Q4 2022

Shares 101,919 Value ($000) $651 Avg Close $7.81 Range $5.42 - $10.41

Q3 2022

Shares 60,818 Value ($000) $583 Avg Close $11.53 Range $9.46 - $13.44

Q2 2022

Shares 130,117 Value ($000) $1,436 Avg Close $13.10 Range $6.18 - $18.73

Q1 2022

Shares 311,320 Value ($000) $5,183 Avg Close $15.46 Range $12.18 - $19.66

Q4 2021

Shares 169,617 Value ($000) $3,238 Avg Close $22.02 Range $15.94 - $27.96

Q3 2021

Shares 112,234 Value ($000) $2,768 Avg Close $23.56 Range $20.19 - $27.01

Q2 2021

Shares 131,996 Value ($000) $3,434 Avg Close $25.99 Range $15.88 - $33.99

Q1 2021

Shares 83,387 Value ($000) $2,640 Avg Close $41.45 Range $27.75 - $54.21

Q4 2020

Shares 103,137 Value ($000) $4,786 Avg Close $39.70 Range $24.67 - $52.43

Q3 2020

Shares 173,508 Value ($000) $5,712 Avg Close $30.66 Range $26.75 - $36.93

Q2 2020

Shares 390,498 Value ($000) $10,719 Avg Close $32.88 Range $26.34 - $41.49

Q1 2020

Shares 62,613 Value ($000) $1,874 Avg Close $26.51 Range $18.70 - $38.92

Q4 2019

Shares 29,255 Value ($000) $810 Avg Close $22.75 Range $17.78 - $29.68

Q3 2019

Shares 32,982 Value ($000) $600 Avg Close $22.11 Range $17.67 - $26.59

Q2 2019

Shares 42,724 Value ($000) $1,048 Avg Close $15.06 Range $9.52 - $25.50

Q3 2017

Shares 21,204 Value ($000) $164 Avg Close $6.33 Range $4.45 - $8.60

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,583,810	$9,784	$2.31	$1.76 - $2.99
Q3 2025	1,413,662	$3,068	$2.36	$1.67 - $4.33
Q2 2025	2,007,571	$3,453	$2.49	$1.64 - $3.73
Q1 2025	121,090	$403	$5.16	$3.19 - $8.15
Q4 2024	295,228	$2,185	$9.27	$7.05 - $12.51
Q3 2024	116,970	$1,098	$9.47	$7.11 - $12.50
Q2 2024	1,030,312	$8,263	$10.72	$7.59 - $14.77
Q1 2024	1,021,067	$15,132	$11.64	$7.34 - $18.33
Q4 2023	522,561	$4,248	$5.23	$3.21 - $9.03
Q3 2023	549,915	$2,502	$6.53	$4.36 - $8.82
Q2 2023	402,317	$2,832	$7.16	$5.28 - $9.36
Q1 2023	65,684	$401	$6.90	$5.39 - $8.49
Q4 2022	101,919	$651	$7.81	$5.42 - $10.41
Q3 2022	60,818	$583	$11.53	$9.46 - $13.44
Q2 2022	130,117	$1,436	$13.10	$6.18 - $18.73
Q1 2022	311,320	$5,183	$15.46	$12.18 - $19.66
Q4 2021	169,617	$3,238	$22.02	$15.94 - $27.96
Q3 2021	112,234	$2,768	$23.56	$20.19 - $27.01
Q2 2021	131,996	$3,434	$25.99	$15.88 - $33.99
Q1 2021	83,387	$2,640	$41.45	$27.75 - $54.21
Q4 2020	103,137	$4,786	$39.70	$24.67 - $52.43
Q3 2020	173,508	$5,712	$30.66	$26.75 - $36.93
Q2 2020	390,498	$10,719	$32.88	$26.34 - $41.49
Q1 2020	62,613	$1,874	$26.51	$18.70 - $38.92
Q4 2019	29,255	$810	$22.75	$17.78 - $29.68
Q3 2019	32,982	$600	$22.11	$17.67 - $26.59
Q2 2019	42,724	$1,048	$15.06	$9.52 - $25.50
Q3 2017	21,204	$164	$6.33	$4.45 - $8.60