ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

FRANKLIN RESOURCES INC's Holding History (CIK: 0000038777)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 1,972,454 Value ($000) $79,726 Avg Close — Range —
Q2 2015
Shares 1,969,983 Value ($000) $113,373 Avg Close — Range —
Q1 2015
Shares 1,729,658 Value ($000) $110,128 Avg Close — Range —
Q4 2014
Shares 2,067,949 Value ($000) $127,676 Avg Close — Range —
Q3 2014
Shares 2,083,967 Value ($000) $80,921 Avg Close — Range —
Q2 2014
Shares 1,951,518 Value ($000) $67,230 Avg Close — Range —
Q1 2014
Shares 2,109,983 Value ($000) $91,172 Avg Close — Range —
Q4 2013
Shares 1,736,654 Value ($000) $69,188 Avg Close — Range —
Q3 2013
Shares 1,955,580 Value ($000) $73,412 Avg Close — Range —
Q2 2013
Shares 1,831,340 Value ($000) $49,208 Avg Close — Range —