ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

AMERIPRISE FINANCIAL INC's Holding History (CIK: 0000820027)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 157,975 Value ($000) $6,368 Avg Close — Range —
Q2 2015
Shares 53,347 Value ($000) $3,070 Avg Close — Range —
Q1 2015
Shares 132,505 Value ($000) $8,436 Avg Close — Range —
Q4 2014
Shares 48,726 Value ($000) $3,008 Avg Close — Range —
Q3 2014
Shares 7,003 Value ($000) $272 Avg Close — Range —
Q2 2014
Shares 1,948 Value ($000) $67 Avg Close — Range —
Q1 2014
Shares 376,647 Value ($000) $16,277 Avg Close — Range —
Q4 2013
Shares 255,090 Value ($000) $10,163 Avg Close — Range —
Q3 2013
Shares 8,064 Value ($000) $302 Avg Close — Range —
Q2 2013
Shares 8,274 Value ($000) $222 Avg Close — Range —