ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

STRS OHIO's Holding History (CIK: 0000820478)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 2,111 Value ($000) $85 Avg Close — Range —
Q2 2015
Shares 2,453 Value ($000) $141 Avg Close — Range —
Q1 2015
Shares 32,753 Value ($000) $2,085 Avg Close — Range —
Q4 2014
Shares 30,200 Value ($000) $1,865 Avg Close — Range —
Q3 2014
Shares 26,200 Value ($000) $1,017 Avg Close — Range —
Q2 2014
Shares 23,700 Value ($000) $816 Avg Close — Range —
Q1 2014
Shares 26,000 Value ($000) $1,123 Avg Close — Range —
Q4 2013
Shares 26,700 Value ($000) $1,064 Avg Close — Range —
Q3 2013
Shares 32,200 Value ($000) $1,209 Avg Close — Range —
Q2 2013
Shares 22,800 Value ($000) $613 Avg Close — Range —