ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

PANAGORA ASSET MANAGEMENT INC's Holding History (CIK: 0000883677)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 123,153 Value ($000) $4,978 Avg Close — Range —
Q2 2015
Shares 468,674 Value ($000) $26,972 Avg Close — Range —
Q1 2015
Shares 498,653 Value ($000) $31,749 Avg Close — Range —
Q4 2014
Shares 479,135 Value ($000) $29,582 Avg Close — Range —
Q3 2014
Shares 455,754 Value ($000) $17,697 Avg Close — Range —
Q2 2014
Shares 468,676 Value ($000) $16,146 Avg Close — Range —
Q1 2014
Shares 437,284 Value ($000) $18,895 Avg Close — Range —
Q4 2013
Shares 522,426 Value ($000) $20,813 Avg Close — Range —
Q3 2013
Shares 528,111 Value ($000) $19,825 Avg Close — Range —
Q2 2013
Shares 751,921 Value ($000) $20,204 Avg Close — Range —