ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

TUDOR INVESTMENT CORP ET AL's Holding History (CIK: 0000923093)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 32,507 Value ($000) $1,871 Avg Close — Range —
Q1 2015
Shares 6,390 Value ($000) $407 Avg Close — Range —
Q4 2014
Shares 6,473 Value ($000) $400 Avg Close — Range —