ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

BANK OF MONTREAL /CAN/'s Holding History (CIK: 0000927971)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 56,554 Value ($000) $2,287 Avg Close — Range —
Q2 2015
Shares 187,176 Value ($000) $10,773 Avg Close — Range —
Q1 2015
Shares 50,406 Value ($000) $3,209 Avg Close — Range —
Q4 2014
Shares 50,080 Value ($000) $3,092 Avg Close — Range —
Q3 2014
Shares 38,556 Value ($000) $1,496 Avg Close — Range —
Q2 2014
Shares 36,739 Value ($000) $1,267 Avg Close — Range —
Q1 2014
Shares 49,287 Value ($000) $2,130 Avg Close — Range —
Q4 2013
Shares 35,330 Value ($000) $1,408 Avg Close — Range —
Q3 2013
Shares 16,559 Value ($000) $622 Avg Close — Range —
Q2 2013
Shares 30,534 Value ($000) $820 Avg Close — Range —