ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

FORT WASHINGTON INVESTMENT ADVISORS INC /OH/'s Holding History (CIK: 0001009016)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 5,200 Value ($000) $299 Avg Close — Range —
Q1 2015
Shares 5,200 Value ($000) $331 Avg Close — Range —
Q4 2014
Shares 5,200 Value ($000) $321 Avg Close — Range —