ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

OAK RIDGE INVESTMENTS LLC's Holding History (CIK: 0001054554)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 179,040 Value ($000) $7,237 Avg Close — Range —
Q2 2015
Shares 179,564 Value ($000) $10,334 Avg Close — Range —
Q1 2015
Shares 180,508 Value ($000) $11,493 Avg Close — Range —
Q4 2014
Shares 180,701 Value ($000) $11,157 Avg Close — Range —