ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

MARSICO CAPITAL MANAGEMENT LLC's Holding History (CIK: 0001055966)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 131,190 Value ($000) $5,302 Avg Close — Range —
Q1 2014
Shares 176,633 Value ($000) $7,632 Avg Close — Range —