ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Voya Investment Management LLC's Holding History (CIK: 0001068837)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 54,785 Value ($000) $2,214 Avg Close — Range —
Q2 2015
Shares 55,244 Value ($000) $3,180 Avg Close — Range —
Q1 2015
Shares 423,053 Value ($000) $26,936 Avg Close — Range —
Q4 2014
Shares 583,258 Value ($000) $36,011 Avg Close — Range —
Q3 2014
Shares 576,237 Value ($000) $22,375 Avg Close — Range —
Q2 2014
Shares 298,812 Value ($000) $10,294 Avg Close — Range —
Q1 2014
Shares 66,412 Value ($000) $2,870 Avg Close — Range —
Q4 2013
Shares 66,412 Value ($000) $2,646 Avg Close — Range —
Q3 2013
Shares 64,658 Value ($000) $2,427 Avg Close — Range —
Q2 2013
Shares 64,658 Value ($000) $1,737 Avg Close — Range —