ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

D.A. DAVIDSON & CO.'s Holding History (CIK: 0001080107)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 16,590 Value ($000) $668 Avg Close — Range —
Q2 2015
Shares 16,219 Value ($000) $931 Avg Close — Range —
Q1 2015
Shares 15,555 Value ($000) $989 Avg Close — Range —
Q4 2014
Shares 22,037 Value ($000) $1,358 Avg Close — Range —
Q3 2014
Shares 29,446 Value ($000) $1,142 Avg Close — Range —
Q2 2014
Shares 27,798 Value ($000) $956 Avg Close — Range —
Q1 2014
Shares 15,819 Value ($000) $682 Avg Close — Range —
Q4 2013
Shares 19,807 Value ($000) $787 Avg Close — Range —
Q3 2013
Shares 18,671 Value ($000) $699 Avg Close — Range —
Q2 2013
Shares 18,192 Value ($000) $488 Avg Close — Range —