ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

MOODY NATIONAL BANK TRUST DIVISION's Holding History (CIK: 0001092903)

Note: Option positions (PUT/CALL) are excluded.

Q4 2014
Shares 36,852 Value ($000) $2,275 Avg Close — Range —
Q3 2014
Shares 15,102 Value ($000) $586 Avg Close — Range —
Q2 2014
Shares 7,407 Value ($000) $255 Avg Close — Range —
Q1 2014
Shares 37,204 Value ($000) $1,608 Avg Close — Range —
Q4 2013
Shares 74,304 Value ($000) $2,960 Avg Close — Range —
Q3 2013
Shares 74,304 Value ($000) $2,789 Avg Close — Range —
Q2 2013
Shares 77,361 Value ($000) $2,079 Avg Close — Range —