ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

PRINCIPAL FINANCIAL GROUP INC's Holding History (CIK: 0001126328)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 21,895 Value ($000) $885 Avg Close — Range —
Q2 2015
Shares 10,398 Value ($000) $598 Avg Close — Range —
Q1 2015
Shares 21,791 Value ($000) $1,388 Avg Close — Range —
Q4 2014
Shares 21,887 Value ($000) $1,351 Avg Close — Range —
Q3 2014
Shares 21,981 Value ($000) $854 Avg Close — Range —
Q2 2014
Shares 24,439 Value ($000) $842 Avg Close — Range —
Q1 2014
Shares 35,053 Value ($000) $1,515 Avg Close — Range —
Q4 2013
Shares 35,374 Value ($000) $1,409 Avg Close — Range —
Q3 2013
Shares 35,330 Value ($000) $1,326 Avg Close — Range —
Q2 2013
Shares 37,302 Value ($000) $1,002 Avg Close — Range —