ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

NOMURA HOLDINGS INC's Holding History (CIK: 0001163653)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 70,055 Value ($000) $4,031 Avg Close — Range —
Q1 2015
Shares 22,600 Value ($000) $1,438 Avg Close — Range —
Q2 2014
Shares 8,393 Value ($000) $289 Avg Close — Range —
Q4 2013
Shares 10,591 Value ($000) $423 Avg Close — Range —
Q3 2013
Shares 12,482 Value ($000) $469 Avg Close — Range —
Q1 2013
Shares 21,330 Value ($000) $363 Avg Close — Range —
Q4 2012
Shares 25,100 Value ($000) $260 Avg Close — Range —