ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

SOMERVILLE KURT F's Holding History (CIK: 0001215208)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 28,802 Value ($000) $1,163 Avg Close — Range —
Q2 2015
Shares 28,907 Value ($000) $1,664 Avg Close — Range —
Q1 2015
Shares 28,762 Value ($000) $1,832 Avg Close — Range —
Q4 2014
Shares 24,662 Value ($000) $1,523 Avg Close — Range —
Q3 2014
Shares 10,105 Value ($000) $393 Avg Close — Range —
Q2 2014
Shares 9,960 Value ($000) $342 Avg Close — Range —