ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

ALPINE WOODS CAPITAL INVESTORS, LLC's Holding History (CIK: 0001226886)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 10,000 Value ($000) $404 Avg Close — Range —
Q2 2015
Shares 10,000 Value ($000) $576 Avg Close — Range —
Q1 2015
Shares 10,000 Value ($000) $637 Avg Close — Range —
Q4 2014
Shares 10,000 Value ($000) $617 Avg Close — Range —
Q3 2014
Shares 20,000 Value ($000) $777 Avg Close — Range —
Q2 2014
Shares 20,010 Value ($000) $689 Avg Close — Range —