ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Advisors Asset Management, Inc.'s Holding History (CIK: 0001297376)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 14,252 Value ($000) $576 Avg Close — Range —
Q2 2015
Shares 11,843 Value ($000) $682 Avg Close — Range —
Q1 2015
Shares 6,694 Value ($000) $426 Avg Close — Range —
Q4 2014
Shares 2,645 Value ($000) $163 Avg Close — Range —
Q3 2014
Shares 2,754 Value ($000) $107 Avg Close — Range —
Q2 2014
Shares 2,701 Value ($000) $93 Avg Close — Range —
Q1 2014
Shares 765 Value ($000) $33 Avg Close — Range —