ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Kidder Stephen W's Holding History (CIK: 0001314377)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 5,880 Value ($000) $239 Avg Close — Range —
Q2 2015
Shares 5,580 Value ($000) $321 Avg Close — Range —
Q1 2015
Shares 5,580 Value ($000) $356 Avg Close — Range —
Q4 2014
Shares 4,780 Value ($000) $296 Avg Close — Range —