ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Calamos Advisors LLC's Holding History (CIK: 0001316507)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 138,160 Value ($000) $5,584 Avg Close — Range —
Q2 2015
Shares 138,160 Value ($000) $7,951 Avg Close — Range —
Q1 2015
Shares 44,530 Value ($000) $2,835 Avg Close — Range —
Q4 2014
Shares 7,140 Value ($000) $441 Avg Close — Range —
Q3 2014
Shares 14,850 Value ($000) $577 Avg Close — Range —
Q2 2014
Shares 10,150 Value ($000) $350 Avg Close — Range —