ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Manchester Capital Management LLC's Holding History (CIK: 0001393389)

Note: Option positions (PUT/CALL) are excluded.

Q4 2014
Shares 4,304 Value ($000) $266 Avg Close — Range —
Q3 2014
Shares 4,304 Value ($000) $167 Avg Close — Range —
Q1 2014
Shares 3,639 Value ($000) $157 Avg Close — Range —
Q4 2013
Shares 3,848 Value ($000) $153 Avg Close — Range —
Q3 2013
Shares 3,848 Value ($000) $144 Avg Close — Range —