ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

MACQUARIE GROUP LTD's Holding History (CIK: 0001418333)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 1,741 Value ($000) $70 Avg Close — Range —
Q2 2015
Shares 45,084 Value ($000) $2,595 Avg Close — Range —
Q1 2015
Shares 185,081 Value ($000) $11,784 Avg Close — Range —
Q4 2014
Shares 125,415 Value ($000) $7,743 Avg Close — Range —
Q3 2014
Shares 86,566 Value ($000) $3,361 Avg Close — Range —