ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Cambridge Investment Research Advisors, Inc.'s Holding History (CIK: 0001419186)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 8,090 Value ($000) $327 Avg Close — Range —
Q2 2015
Shares 7,031 Value ($000) $405 Avg Close — Range —
Q1 2015
Shares 6,374 Value ($000) $406 Avg Close — Range —
Q4 2014
Shares 7,296 Value ($000) $450 Avg Close — Range —
Q3 2014
Shares 6,667 Value ($000) $259 Avg Close — Range —
Q2 2014
Shares 6,722 Value ($000) $232 Avg Close — Range —