ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Voya Financial Advisors, Inc.'s Holding History (CIK: 0001424367)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 7,180 Value ($000) $273 Avg Close — Range —
Q2 2015
Shares 6,400 Value ($000) $359 Avg Close — Range —
Q1 2015
Shares 6,400 Value ($000) $415 Avg Close — Range —