ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

CAPSTONE INVESTMENT ADVISORS, LLC's Holding History (CIK: 0001426196)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 72,000 Value ($000) $4,584 Avg Close — Range —
Q4 2014
Shares 133,124 Value ($000) $8,219 Avg Close — Range —