ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

First City Capital Management, Inc.'s Holding History (CIK: 0001427350)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 6,665 Value ($000) $269,399 Avg Close — Range —
Q2 2015
Shares 5,630 Value ($000) $324,007 Avg Close — Range —
Q1 2015
Shares 4,775 Value ($000) $304,024 Avg Close — Range —
Q4 2014
Shares 4,800 Value ($000) $296,352 Avg Close — Range —
Q3 2014
Shares 4,800 Value ($000) $186,384 Avg Close — Range —
Q2 2014
Shares 4,800 Value ($000) $165,360 Avg Close — Range —
Q1 2014
Shares 4,800 Value ($000) $207,408 Avg Close — Range —
Q3 2013
Shares 5,500 Value ($000) $206,470 Avg Close — Range —