ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

OXFORD ASSET MANAGEMENT LLP's Holding History (CIK: 0001438284)

Note: Option positions (PUT/CALL) are excluded.

Q3 2013
Shares 298,197 Value ($000) $11,194 Avg Close — Range —
Q2 2013
Shares 360,836 Value ($000) $9,696 Avg Close — Range —