ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Quantitative Investment Management, LLC's Holding History (CIK: 0001445911)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 65,300 Value ($000) $2,639 Avg Close — Range —
Q1 2014
Shares 9,800 Value ($000) $423 Avg Close — Range —