ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Mitsubishi UFJ Kokusai Asset Management Co., Ltd.'s Holding History (CIK: 0001466546)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 14,029 Value ($000) $567 Avg Close — Range —
Q2 2015
Shares 14,201 Value ($000) $817 Avg Close — Range —
Q1 2015
Shares 14,963 Value ($000) $953 Avg Close — Range —