ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Zweig-DiMenna Associates LLC's Holding History (CIK: 0001533950)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 4,200 Value ($000) $242 Avg Close — Range —
Q1 2014
Shares 5,100 Value ($000) $220 Avg Close — Range —