ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Allianz Asset Management GmbH's Holding History (CIK: 0001535323)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 4,805 Value ($000) $306 Avg Close — Range —
Q2 2014
Shares 110,000 Value ($000) $3,790 Avg Close — Range —
Q1 2014
Shares 359,670 Value ($000) $15,541 Avg Close — Range —
Q4 2013
Shares 590,225 Value ($000) $23,514 Avg Close — Range —
Q3 2013
Shares 368,485 Value ($000) $13,833 Avg Close — Range —
Q2 2013
Shares 1,097,727 Value ($000) $29,496 Avg Close — Range —