ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

PDT Partners, LLC's Holding History (CIK: 0001564702)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 27,303 Value ($000) $1,104 Avg Close — Range —
Q2 2015
Shares 111,910 Value ($000) $6,440 Avg Close — Range —
Q2 2014
Shares 155,125 Value ($000) $5,344 Avg Close — Range —
Q4 2013
Shares 6,084 Value ($000) $242 Avg Close — Range —
Q3 2013
Shares 77,172 Value ($000) $2,897 Avg Close — Range —
Q2 2013
Shares 51,856 Value ($000) $1,393 Avg Close — Range —