ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Rhenman & Partners Asset Management AB's Holding History (CIK: 0001599882)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 80,000 Value ($000) $3,234 Avg Close — Range —
Q2 2015
Shares 94,000 Value ($000) $5,410 Avg Close — Range —
Q1 2015
Shares 102,000 Value ($000) $6,494 Avg Close — Range —
Q4 2014
Shares 42,000 Value ($000) $2,593 Avg Close — Range —
Q3 2014
Shares 58,000 Value ($000) $2,252 Avg Close — Range —
Q2 2014
Shares 36,000 Value ($000) $1,240 Avg Close — Range —