ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Tradewinds Capital Management, LLC's Holding History (CIK: 0001616026)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 170 Value ($000) $7 Avg Close — Range —
Q2 2015
Shares 170 Value ($000) $10 Avg Close — Range —
Q1 2015
Shares 100 Value ($000) $6 Avg Close — Range —
Q4 2014
Shares 110 Value ($000) $7 Avg Close — Range —