ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Garde Capital, Inc.'s Holding History (CIK: 0001616328)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 4,000 Value ($000) $230 Avg Close — Range —
Q1 2015
Shares 4,000 Value ($000) $255 Avg Close — Range —
Q4 2014
Shares 4,000 Value ($000) $247 Avg Close — Range —