ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

Brick & Kyle, Associates's Holding History (CIK: 0001632253)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 300 Value ($000) $12 Avg Close — Range —
Q2 2015
Shares 300 Value ($000) $17 Avg Close — Range —
Q1 2015
Shares 300 Value ($000) $19 Avg Close — Range —
Q4 2014
Shares 150 Value ($000) $9 Avg Close — Range —