ISIS PHARMACEUTICALS INC

CUSIP: 464337AE4 Class: CNV

GOLDMAN SACHS GROUP INC's Holding History (CIK: 0000886982)

Note: Option positions (PUT/CALL) are excluded.

Q2 2012
Shares 14,000,000 Value ($000) $14,175 Avg Close — Range —
Q1 2012
Shares 14,750,000 Value ($000) $14,290 Avg Close — Range —