ISIS PHARMACEUTICALS INC DEL

CUSIP: 464337AG9 Class: NOTE 2.750%10/0

DEUTSCHE BANK AG\'s Holding History (CIK: 0000948046)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 4,943,000 Value ($000) $18,987 Avg Close — Range —
Q4 2014
Shares 9,943,000 Value ($000) $36,944 Avg Close — Range —
Q3 2014
Shares 16,943,000 Value ($000) $40,959 Avg Close — Range —
Q2 2014
Shares 13,023,000 Value ($000) $28,666 Avg Close — Range —
Q1 2014
Shares 4,947,000 Value ($000) $13,272 Avg Close — Range —
Q4 2013
Shares 4,666,000 Value ($000) $11,599 Avg Close — Range —
Q3 2013
Shares 4,666,000 Value ($000) $10,909 Avg Close — Range —