ISIS PHARMACEUTICALS INC DEL

CUSIP: 464337AG9 Class: NOTE 2.750%10/0

Clearbridge Investments, LLC's Holding History (CIK: 0001348883)

Note: Option positions (PUT/CALL) are excluded.

Q3 2014
Shares 2,280,000 Value ($000) $5,560 Avg Close — Range —
Q2 2014
Shares 4,050,000 Value ($000) $90 Avg Close — Range —
Q1 2014
Shares 1,700,000 Value ($000) $4,547 Avg Close — Range —